Author: James Fishman

In a fascinating new study from Washington University School of Medicine in St. Louis, the greatest benefit of weight loss in obese patients apparently comes from losing just 5% of their body weight. Published online on February 22 in the journal Cell Metabolism, they found that this relatively small weight loss lowered patients’ risk for diabetes and cardiovascular disease while improving the metabolic function in liver, fat and muscle tissue.

As the principal investigator Samuel Klein, MD, director of Washington University’s Center for Human Nutrition said, “Our findings demonstrate that you get the biggest bang for your buck with 5 percent weight loss. The current guidelines for treating obesity recommend a 5 to 10 percent weight loss, but losing 5 percent of your body weight is much easier than losing 10 percent. So it may make sense for patients to aim at the easier target.”

The study included asking 40 obese individuals to either maintain their body weight or start a diet to lose 5-15% of their body weight. This is thought to be the first time that a trial has separated weight loss outcomes and distinguished between a 5% loss and a 10% or greater loss.

With the 19 volunteers who lost 5% of their body weight, the function of insulin-secreting beta cells improved, the insulin sensitivity in fat tissues improved, the liver and skeletal muscle tissue improved and there was a decrease in total body fat and less fat in the liver.

For the nine participants who then continued to lose weight until the 15% mark, they had some improvements but not in all areas. Their bet cell function and insulin sensitivity in muscle tissue improved, but neither their insulin sensitivity in the liver or the adipose tissue continued to improve.
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What they found from this is that, as Klein explained, “Muscle tissue responds much more to continued weight loss, but liver and adipose tissue have pretty much achieved their maximum benefit at 5 percent weight loss.”

Certainly, more research is needed by the initial findings are quite interesting. Klein would like to also study people who have diabetes.

Obviously, having a healthy weight is important. But it’s interesting to note how much the first 5% of that weight loss can have an impact.

Interestingly, it might be more important for you to chat about your latest book than to get your body moving, say researchers looking at retirement needs. Scientists have found that maintaining social links in old age may help you to live longer.

Tracking a group of 424 English men and women during their first six years of retirement, the scientists found a six-fold difference in mortality rates between the people who were members of at least two social groups from before their retirement and those who stopped attending clubs. The researchers, from the University of Queensland in Australia published their findings in BMJ Open, a UK medical journal.

As they explained, “Retiring from work constitutes a major life transition that most people experience at some point in the course of their life, posing significant challenges to health and wellbeing.”

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They found that the number of social relationships that people maintain during their retirement can have more of an impact on life expectancy than exercise, smoking or drinking.

The overall take-away, as explained by the researchers was that: “Practical interventions should focus on helping retirees to maintain their sense of purpose and belonging by assisting them to connect to groups and communities that are meaningful to them.”

Researchers at the Texas Christian University have found that the amount that we eat when we aren’t hungry as adults is directly linked to our family’s income when we were kids.

As researcher Sarah Hill explained, “Our research suggests that people who grew up in relatively impoverished environments may have a harder time controlling food intake and managing their body weight than those who grew up in wealthier environments.”

Published in the journal Psychological Science, the article explains that the researchers did a number of experiments to come to their conclusion. First, 31 non-obese women each received a bowl of chocolate chip cookies and one of pretzels and were told to sample and rate the products. Then, when they finished their ratings, they were told that they could eat as much as they wanted to while waiting for part two. They were then asked to describe their economic situation growing up. Researchers found that women from poorer backgrounds ate more of the goodies than those who came from wealthier homes.
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Two more experiments replicated the findings and leave room to ask more questions about need versus desire and the way that our background forms our impulsivity and needs.